Cyclophosphamide Duration Across Clinical Indications

ANCA‑Associated Vasculitis

• Guidelines for ANCA‑associated vasculitis advise continuous cyclophosphamide administration for 3–6 months, which is markedly longer than the 2–3 day high‑dose pulse used in severe paraquat poisoning. 1

Pemphigus

• Therapeutic regimens for pemphigus employ multi‑phase cyclophosphamide courses lasting 12 months or more, again far exceeding the brief pulse schedule recommended for paraquat poisoning. [2] [3] 4