Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/16/2025

Characteristics of Normal and Abnormal Popliteal Lymph Nodes

Imaging Characteristics

  • Benign lymph nodes typically have smooth, well-defined borders with uniform and homogeneous attenuation, according to the American College of Radiology 1
  • The presence of a central fatty hilum is reassuring for benign etiology, as stated by the American College of Radiology 1
  • The presence of a central fatty hilum is reassuring for benign etiology, with a strength of evidence supported by multiple sources, including the Journal of the American College of Radiology 1, 2

REFERENCES

2

Lymph Node Size Requiring Workup [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025