Propranolol Administration and Monitoring

Administration Considerations

• Propranolol can be administered orally in immediate-release formulations, with a typical administration schedule of 3-4 times daily due to its relatively short half-life (3-6 hours) 1
• Extended-release formulations have a longer half-life (8-20 hours) but are less commonly used for acute akathisia management 1

Monitoring and Safety Considerations

• Blood pressure and heart rate should be monitored during treatment, particularly at initiation, according to the American Heart Association guidelines 1
• Propranolol is contraindicated in patients with asthma, obstructive airway disease, decompensated heart failure, and certain cardiac conduction abnormalities, as recommended by the American College of Cardiology 1