Triamcinolone Acetonide Therapy

Intralesional Injections

• Triamcinolone acetonide (5-10 mg/mL) can be injected for treating patchy alopecia areata, with injections being most suitable for limited patches of hair loss and cosmetically sensitive areas like eyebrows 1, 2
• A small injection of 0.05-0.1 mL can produce a tuft of hair growth approximately 0.5 cm in diameter 2

Acne Treatment

• Intralesional injection of triamcinolone acetonide is commonly used for managing larger, nodular acne lesions, providing rapid improvement and decreased pain in inflammatory acne nodules 3

Administration Considerations

• The American Academy of Dermatology recommends using the minimum effective amount to control symptoms 4
• Apply sparingly to skin folds and intertriginous areas to minimize the risk of atrophy 4

Potential Adverse Effects

• Skin atrophy at injection sites is a consistent side effect of intralesional corticosteroid therapy, particularly with triamcinolone 2
• Folliculitis is a common side effect when using potent topical steroids 1

Best Practices for Use

• The American Academy of Dermatology recommends gradual reduction in application frequency after clinical improvement 4
• Consider twice-weekly application for maintenance therapy to maintain disease control while minimizing adverse effects 4

Risk of Intralesional Steroid Use in Periocular Areas

Safety Considerations

• Intralesional triamcinolone should never be administered in peri‑ocular regions because of rare but potentially catastrophic central retinal artery embolization that can cause permanent vision loss【5】.