Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/12/2025

Post-Operative Care for Penile Implant Patients

Infection Prevention and Management

  • The American Urological Association recommends adding an antifungal agent to antibacterial coverage, reducing infection risk by 92% compared to antibacterial agents alone 1
  • Patients should continue perioperative antibiotics as prescribed, recognizing that infection occurs in 1-6% of patients, with higher rates in diabetics 2, 3
  • The use of antibiotic-impregnated/coated devices, antiseptic surgical scrub, no-touch technique, and wound irrigation should be employed during surgery to minimize infection risk 1
  • Diabetic patients have nearly double the infection risk and require more aggressive prophylaxis 1
  • Patients with immunosuppression, prior pelvic radiotherapy, or revision cases need heightened surveillance 4

Identifying and Managing Complications

  • Infection warning signs include increasing pain, fever, wound drainage, erythema, or warmth at the surgical site 2, 3
  • Do not ignore early signs of infection, as device infection can necessitate explantation, cause sexual dysfunction, and result in additional penile length loss 2, 3
  • Inadequate infection prevention by omitting antifungal prophylaxis is a critical error given the 92% risk reduction it provides 1
  • Failure to optimize pre-existing medical comorbidities, particularly diabetes, increases infection risk 1

Follow-Up and Device Management

  • Median follow-up typically occurs at 9 months, though patients without complications may be seen at 13 months 4