Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/10/2025

Eyelid Eversion Techniques and Clinical Applications

Preparation and Procedure

  • Position the patient comfortably with adequate lighting for visualization, as recommended by the American Academy of Ophthalmology 1

Clinical Context for Eyelid Eversion

  • The American Academy of Dermatology recommends daily examination during the acute phase of Stevens-Johnson syndrome/toxic epidermal necrolysis to assess tarsal conjunctiva for inflammation, fibrosis, and signs of allergy 2
  • The American Academy of Ophthalmology suggests routine dry eye evaluation to document tarsal conjunctival status including inflammation, papillary reaction, follicle enlargement, keratinization, subepithelial fibrosis, and scarring 1
  • The American Academy of Ophthalmology recommends blepharitis assessment to evaluate posterior eyelid margin abnormalities and meibomian gland dysfunction 1

What to Examine After Eversion

  • Assess the integrity of the tarsal conjunctiva using topical fluorescein to stain epithelial loss, as recommended by the British Association of Dermatologists 2
  • Evaluate for mucous threads, scarring, erythema, papillary reaction, follicle enlargement, keratinization, subepithelial fibrosis, foreshortening, and symblepharon, as suggested by the American Academy of Ophthalmology 1

Important Caveats

  • Avoid aggressive manipulation in patients with neurotrophic corneas to prevent corneal epithelial injury, as recommended by the American Academy of Ophthalmology, with a strength of evidence level not specified 4