Antibiotic Dosage Guidelines

Introduction to Oxacilina

• The American Heart Association/American College of Cardiology recommends oxacilina 12 grams per day IV divided into 4-6 equal doses (every 4-6 hours) for infections such as endocarditis by Staphylococcus aureus 1, 2

Dosage Recommendations

• The FDA recommends the following dosages for oxacilina:

Special Considerations

• For endocarditis by Staphylococcus aureus, the American Heart Association/American College of Cardiology guidelines are based on evidence from 2008, recommending oxacilina 12 grams per day IV divided into 4-6 equal doses (every 4-6 hours) 1, 2

Administration and Monitoring

• Although not directly stated with a citation, the importance of monitoring and adjusting dosages, especially in patients with renal insufficiency, is a critical consideration in antibiotic therapy.