Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/7/2025

Cetirizine Use During Breastfeeding

Clinical Recommendations

  • The European Respiratory Society recommends loratadine or cetirizine as preferred antihistamines during breastfeeding, as they have been most extensively studied 1
  • Antihistamines may theoretically reduce milk production, though this has not been demonstrated clinically with cetirizine, according to the European Respiratory Society guidelines 1

Important Caveats

  • In moderate renal impairment, the cetirizine dose should be halved, as recommended by the British Journal of Dermatology 2
  • Cetirizine should be avoided entirely in severe renal impairment, according to the British Journal of Dermatology 2