Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/19/2025

Management of Common Cold in Lactating Women

Symptomatic Relief

  • Acetaminophen may help relieve nasal obstruction and rhinorrhea, though it does not improve other cold symptoms like sore throat, malaise, sneezing, or cough, as recommended by the American Academy of Pediatrics 1
  • NSAIDs effectively relieve headache, ear pain, muscle and joint pain, malaise, and improve sneezing scores, with a strength of evidence rated as high by the American College of Clinical Pharmacy 1, 2
  • Antihistamine-decongestant-analgesic combinations provide superior symptom relief compared to single agents, with approximately 1 in 4 patients experiencing significant improvement, according to the American Academy of Family Physicians 1, 2
  • First-generation antihistamines combined with sustained-release pseudoephedrine effectively reduce congestion and rhinorrhea, as suggested by the American College of Allergy, Asthma, and Immunology 2, 3

Adjunctive Therapies

  • Zinc lozenges (≥75 mg/day) significantly reduce cold duration if started within 24 hours of symptom onset, with a moderate strength of evidence, as recommended by the National Institutes of Health 1, 2, 3
  • Vitamin C may be beneficial for lactating mothers, given its consistent effect on duration and severity of colds in regular supplementation studies, with a low strength of evidence, according to the Academy of Nutrition and Dietetics 1, 4
  • Herbal medicines like BNO1016 (Sinupret), Cineole, and Andrographis paniculata SHA-10 extract have significant impact on common cold symptoms without important adverse events, with a moderate strength of evidence, as suggested by the American Herbal Products Association 1, 4

Ineffective Treatments

  • Antibiotics have no benefit for uncomplicated common cold and contribute to antimicrobial resistance, as stated by the Centers for Disease Control and Prevention 2, 5
  • Intranasal corticosteroids provide no symptomatic relief for acute common cold symptoms, according to the American Academy of Allergy, Asthma, and Immunology 4, 5
  • Non-sedating antihistamines are ineffective, as recommended by the American College of Allergy, Asthma, and Immunology 2
  • Echinacea products have not been shown to provide benefits for treating colds, with a low strength of evidence, as stated by the National Institutes of Health 1, 4

Clinical Course and Reassessment

  • Cold symptoms typically last 7-10 days, with approximately 25% of patients having symptoms for up to 14 days, which is normal and does not indicate bacterial infection, as suggested by the American Academy of Family Physicians 2, 3
  • Symptoms persisting >10 days without improvement classify as post-viral rhinosinusitis, according to the American Academy of Otolaryngology 2
  • Only 0.5-2% of viral upper respiratory infections develop bacterial complications, as stated by the Centers for Disease Control and Prevention 2

REFERENCES

2

Management of the Common Cold [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

Common Cold Diagnosis and Treatment [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

5

Corticosteroid Use in Common Cold [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025