Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Epirubicin and Ifosfamide Combination Therapy

Urogenital and Long-term Side Effects

  • Ifosfamide can impair renal function and cause Fanconi syndrome in patients, according to the European Society for Medical Oncology 1, 2
  • Ifosfamide can negatively impact bone health in children and adolescents, as reported by the European Society for Medical Oncology 1, 2

Therapeutic Efficacy and Administration

  • The combination of Epirubicin and Ifosfamide is used as an effective chemotherapy for various sarcomas, as recommended by the European Society for Medical Oncology 3, 4, 5