Duloxetine Dosing for Neuropathic Pain Management

Initial Dosing and Titration

• An adequate trial of duloxetine should be at least 4 weeks at the therapeutic dose, according to the Mayo Clinic Proceedings 1, 2

Clinical Pearls

• Patient education should emphasize that pain relief may not be immediate and that a trial and error approach may be needed, as suggested by the Journal of the National Comprehensive Cancer Network 3