Prognostic Value of Neutrophil-to-Lymphocyte Ratio

Cancer Prognosis

• The European Society for Medical Oncology recommends considering Neutrophil-to-Lymphocyte Ratio (NLR) as a prognostic factor in cancer patients, as higher NLR (>3.0) correlates with poorer prognosis in various solid tumors 1
• Elevated NLR is associated with increased mortality in cancer patients, according to the European Respiratory Society 2

Inflammatory Markers

• The European Respiratory Society suggests that inflammatory markers such as CRP and ESR can be used to assess for inflammatory conditions, and NLR can be used in conjunction with these markers to evaluate the severity of inflammation 2

Malignant Pleural Effusions

• The European Respiratory Society recommends using the LENT score, which incorporates NLR, to predict survival in patients with malignant pleural effusions 2, 3, 4
• The British Thoracic Society suggests that NLR is a significant predictor of survival in patients with malignant pleural effusions, and should be included in the LENT score 6

Inflammatory Bowel Disease

• The World Journal of Emergency Surgery suggests that NLR can help predict the presence of intra-abdominal abscess in Crohn's disease patients presenting with acute abdominal pain, according to the World Society of Emergency Surgery 5