Dosing Considerations for Adults with Type 2 Diabetes

Special Dosage Considerations

• The American College of Cardiology suggests considering alternative therapeutic options with a lower risk of hypoglycemia in high-risk patients, such as those with chronic kidney disease, as supported by the Mayo Clinic Proceedings 1, 2
• The American College of Cardiology recommends reducing the dose if HbA1c is well-controlled or if there are frequent episodes of hypoglycemia, as stated in the Journal of the American College of Cardiology 3
• For patients with chronic kidney disease, the Mayo Clinic Proceedings suggests considering alternative medications such as SGLT2 inhibitors or GLP-1 receptor agonists 1, 2