Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/5/2025

Trazodone Use During Pregnancy

Clinical Recommendations

  • For women requiring treatment for both depression and insomnia during pregnancy, bupropion may be considered as an alternative, as it does not seem to be associated with major congenital malformations or other significant adverse obstetrical outcomes, according to the American College of Obstetricians and Gynecologists 1

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