Anuria Definition and Management

Diagnostic Criteria

The National Kidney Foundation defines anuria as a urine production of less than 100 mL in 24 hours, or alternatively, less than 200 mL in 24 hours in certain clinical contexts 1, 2, 3, 4
In peritoneal dialysis, anuria is defined as a urine volume of less than 100 mL/day, or a renal creatinine clearance of less than 1 mL/min 1, 2, 3, 4
Alternatively, some studies use a threshold of less than 200 mL/day to define anuria in patients with peritoneal dialysis 1, 2, 3, 4

In the context of CAR-T cell therapy and cytokine release syndrome, anuria is defined as a urine output of less than 0.3 mL/kg/hour for 24 hours, or less than 0 mL/kg/hour for 12 hours 5

Oliguria is defined as a urine output of less than 0.5 mL/kg/hour for 8 hours in the pediatric population 5

In patients with peritoneal dialysis who develop anuria, the dose of small solute clearance should be measured within the first month of starting dialysis, and subsequently at least every 4 months to adjust the dialysis prescription 1, 2, 3
The minimum target for weekly peritoneal Kt/V is 1.7 or greater in anuric patients on continuous ambulatory peritoneal dialysis (CAPD) 1, 2, 3, 4