Carbetocin for Prevention of Postpartum Hemorrhage in Special Populations

Safety and Efficacy in Specific Patient Groups

• The European Heart Journal recommends carbetocin for cardiac patients as it may be preferable to other uterotonics like methylergonovine, which is contraindicated due to risk of vasoconstriction and hypertension 1
• The American College of Cardiology is not mentioned, however, carbetocin shows better hemodynamic stability than oxytocin with less significant drops in blood pressure, making it potentially safer in women with cardiac or hypertensive disorders, although the specific guideline society is not provided 2