Hematological Derangements in Acute Pancreatitis

Systemic Inflammation and Hematological Changes

• Increasing leucocyte and platelet counts with deranged clotting parameters indicate possible sepsis and represent adverse hematological changes in severe acute pancreatitis, as reported by the Gut society 1, 2
• The systemic inflammatory response with proinflammatory cytokine release contributes to metabolic derangements and bone marrow suppression, according to a study published in a medical journal, although the American Gastroenterological Association was not specified 3