Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/2/2025

Vitamin C Intake Recommendations

Standard Recommendations by Region

  • The European Food Safety Authority recommends a daily intake of 110 mg of vitamin C for men and 95 mg for women, based on maintaining optimal plasma vitamin C concentrations and replacing daily metabolic turnover 2, 3, 1
  • The United States and Canada recommend a daily intake of 90 mg of vitamin C for men and 75 mg for women 2, 1
  • Countries focused on scurvy prevention only, such as the UK, Australia, India, and FAO/WHO, recommend a daily intake of 40-45 mg of vitamin C 2, 3

Populations Requiring Higher Intake

  • Pregnant women require an additional 10-20 mg of vitamin C per day above the baseline intake, for a total of 85-110 mg per day 3
  • Lactating women require an additional 20-60 mg of vitamin C per day above the baseline intake, for a total of 95-150 mg per day 3
  • Older adults may require special attention to ensure adequate vitamin C intake, particularly those in long-term care or with poor dietary intake 4

Upper Safety Limit

  • The Tolerable Upper Intake Level (UL) for vitamin C is 2,000 mg per day for adults, based on the risk of gastrointestinal upset 1, 5

Critical Contraindications

  • Patients with hemochromatosis or iron overload conditions should avoid vitamin C supplements, as they can accelerate iron mobilization and cause fatal cardiac complications 1, 6
  • If vitamin C is medically necessary for patients with iron overload, the dose should be limited to 500 mg per day after physician consultation 6

Minimum vs. Optimal Intake

  • A daily intake of 40-45 mg of vitamin C is sufficient to prevent scurvy, but does not achieve tissue adequacy or optimal health 2, 3, 1
  • A daily intake of 75-110 mg of vitamin C is recommended for tissue saturation and antioxidant protection 2, 3, 1

Practical Considerations

  • Oral absorption of vitamin C is limited at higher doses due to saturation of intestinal transporters, and doses above 200 mg have progressively lower absorption 1
  • Tea consumption with meals can interfere with iron absorption and should be avoided if iron deficiency is a concern 4

REFERENCES

3

Vitamin C Intake Guidelines [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

5

Vitamin C Intake and Potential Adverse Effects [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

6

Vitamin C and Iron Absorption [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025