Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/10/2025

Sheehan Syndrome: Diagnosis and Management Based on Cited Facts

Diagnostic Approach and Management

  • The American College of Obstetricians and Gynecologists guidelines emphasize vigilance for Sheehan syndrome in patients with severe postpartum hemorrhage, particularly when blood loss exceeds 2000 mL or requires massive transfusion, and a detailed obstetric history focusing on postpartum hemorrhage severity, estimated blood loss, need for transfusion, hypotension, or shock is crucial for diagnosis 1

Prevention and Awareness

  • The American College of Obstetricians and Gynecologists recommends maintaining a high index of suspicion for Sheehan syndrome in any woman with a history of postpartum hemorrhage who presents with unexplained fatigue, amenorrhea, or inability to lactate, with an emphasis on patients with severe postpartum hemorrhage 1

REFERENCES

1

placenta accreta spectrum. [LINK]

American Journal of Obstetrics and Gynecology, 2018