Hydroxyzine Dosing and Administration for Anxiety

Special Populations

• For elderly or debilitated patients, lower doses are typically recommended due to increased risk of sedation and other side effects, with consideration for reduced dosing similar to recommendations for benzodiazepines in this population (25-50% reduction) 1, 2, 3

Side Effects and Precautions

• Caution should be exercised when combining hydroxyzine with other CNS depressants, particularly benzodiazepines, as this may increase sedation 1

Important Clinical Considerations

• When prescribing for anxiety, be aware that the onset of action is relatively quick compared to some other anxiolytics like buspirone, according to the American Academy of Family Physicians 4, 5