Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/15/2025

Caffeine Dosage and Administration

Recommendations for Athletes and Sports Performance

  • The British Journal of Sports Medicine recommends a dosage of 3-6 mg/kg body weight of caffeine anhydrous (in pill or powder form) to be consumed approximately 60 minutes before exercise or competition 1
  • A low dose of caffeine (<3 mg/kg body weight, ~200 mg caffeine base) can be given before and during rest periods in a competition along with a carbohydrate source 1

Safety Guidelines

  • The American College of Sports Medicine and other guideline societies suggest that the safe limit for healthy adults is ≤400 mg caffeine base per day (equivalent to ≤800 mg caffeine citrate), although this fact is also reported by Praxis Medical Insights, a more general guideline is: the safe limit for healthy adults is ≤400 mg caffeine base per day (equivalent to ≤800 mg caffeine citrate) 2
  • For children and adolescents: <2.5 mg/kg body weight per day caffeine base (equivalent to <5 mg/kg caffeine citrate) 2
  • For pregnant women: ≤200-300 mg caffeine base per day (equivalent to ≤400-600 mg caffeine citrate) 2
  • High doses of caffeine can cause side effects including anxiety, nausea, insomnia, tremors, tachycardia, and arrhythmia 1

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