Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/15/2025

Keppra Therapy Guidelines

Patient Education and Monitoring

  • The American Academy of Neurology recommends that patients carry medical identification indicating they have epilepsy and are taking antiepileptic medication 1
  • For patients with pre-existing liver disease, the American Association for the Study of Liver Diseases suggests considering monthly liver function tests 2
  • Standard adult dosing begins at 500 mg twice daily with potential increases to 1000-3000 mg/day based on clinical response, as recommended by the American College of Clinical Pharmacology 1
  • The American College of Clinical Pharmacology recommends using seizure diaries to track frequency and patterns of seizures 1

REFERENCES

1

Levetiracetam Management Guidelines [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025