Penile Prosthesis Implantation Procedure

Preoperative Preparation

Patient must be free of urinary tract infection, systemic infection, and cutaneous lesions in the operative area to reduce infection risk 1, 2
Broad-spectrum antibiotics providing both Gram-negative and Gram-positive coverage must be administered before incision (commonly aminoglycosides, vancomycin, cephalosporins, or fluoroquinolones) 1, 3
The operative area should be shaved immediately prior to surgery, not earlier, to prevent small skin cuts that could become infected 1, 4
Thorough skin preparation is performed after shaving 1, 2

Inflatable penile prosthesis is recommended for patients with Peyronie's disease as it allows for modeling to maximize curvature correction 5
For patients with Peyronie's disease and erectile dysfunction, penile prosthesis implantation may be combined with adjunctive procedures such as modeling, plication, or incision/grafting 5
Modern penile implants are MRI-compatible at 1.5 Tesla field strength, with no current manufacturers producing MRI-contraindicated devices 1, 2
Infection rates have been reduced with antibiotic-coated or hydrophilic-coated devices (rates of 1-2%) 6, 7

Patients should be thoroughly counseled regarding post-operative expectations 6
Potential complications include penile edema, hematoma, corporeal injury, urethral injury, and acute urinary retention 6
Infection is a serious complication typically occurring within the first three months after surgery 6

Patients must understand that prosthesis implantation will likely reduce the efficacy of subsequent therapies should they be needed 4, 8