Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/16/2025

Effective PPE Management Protocols

Core Components of PPE Management

  • PPE forms only one part of a comprehensive system to prevent contamination and infection of healthcare workers (HCWs) during patient care 1, 2
  • Additional critical components include decontamination of surfaces/equipment, minimizing unnecessary patient contact, and careful waste management 1, 2
  • PPE must be considered as an integrated system where all components work together to provide consistent protection 3, 4

Proper PPE Selection

  • PPE should be selected based on risk assessment of the specific clinical scenario 3, 5
  • Minimum respiratory protection for COVID-19 and similar infectious diseases should be NIOSH-certified N95 respirators or equivalent that filter 95% of airborne particulates with a diameter of 0.3 microns 4, 6
  • PPE should cover the whole upper body and be disposable whenever possible 1, 2

Training and Education

  • All workers must be trained in proper donning (applying) and doffing (removing) procedures to prevent self-contamination 3, 4
  • Training should occur before patient management and include practice sessions 1, 7
  • A comprehensive Respiratory Protection Program (RPP) must be implemented for respirator use, including proper fit testing 4, 6

Environmental Controls and Zoning

  • Establish clearly defined exposure zones to minimize risk of contamination 3, 5
  • High-risk zones must be clearly demarcated with warning signs 3, 5
  • Ideally, patients should be managed in single, negative pressure rooms with good air exchange rates (>12 exchanges per hour) 1, 2
  • Maintain physical separation of at least 2 meters (6 feet) between workers whenever possible 3, 4

Buddy System and Monitoring

  • Implement a "buddy system" with observers and checklists to ensure proper donning and doffing procedures 1, 2

Physiological Considerations

  • Working in full PPE poses physiological risks including dehydration and heat stress 3, 4
  • Limit work shift duration and implement proper decontamination procedures during breaks 3, 4

Disposal and Decontamination

  • PPE should be disposed of appropriately immediately after removal (doffing) 1, 2
  • Follow established disinfection recommendations for surfaces and reusable equipment 3, 5

Common Pitfalls and How to Avoid Them

  • Improper doffing technique is a major source of self-contamination, ensure proper training and use of the buddy system to monitor technique 1
  • Inadequate fit testing can significantly reduce protection, ensure proper fit testing is performed initially and annually 4, 6
  • Confusing surgical masks with respirators can lead to inadequate protection, as surgical masks do not provide adequate protection against airborne pathogens 8

REFERENCES

3

24th collegium ramazzini statement. prevention of work-related infection in the covid-19 pandemic. [LINK]

International Journal of Occupational and Environmental Medicine, 2020

4

24th collegium ramazzini statement. prevention of work-related infection in the covid-19 pandemic. [LINK]

International Journal of Occupational and Environmental Medicine, 2020

5

24th collegium ramazzini statement. prevention of work-related infection in the covid-19 pandemic. [LINK]

International Journal of Occupational and Environmental Medicine, 2020

6

24th collegium ramazzini statement. prevention of work-related infection in the covid-19 pandemic. [LINK]

International Journal of Occupational and Environmental Medicine, 2020

8

N95 Mask Clearance for Patients with Respiratory Conditions [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025