Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/8/2025

Cardiac Arrest Treatment Following Open Heart Surgery

Initial Response Algorithm

  • External chest compressions should be performed immediately if emergency resternotomy is not immediately available 1
  • For witnessed VF/VT arrest, perform immediate defibrillation; if unsuccessful within 1 minute, initiate CPR 1
  • For asystolic or bradycardic arrest with pacer wires already in place, attempt immediate pacing; if unsuccessful within 1 minute, initiate CPR 1
  • Rapidly identify and correct potential causes of arrest including tamponade, pneumothorax, valve dysfunction, graft occlusion, or bleeding 2

Specialized Interventions

Resternotomy Considerations

  • Early resternotomy is reasonable in an appropriately staffed and equipped ICU (Class 2a recommendation) 1, 2
  • Open-chest CPR is useful if cardiac arrest develops during surgery when the chest is already open or in the early postoperative period 1, 4
  • Resternotomy should be performed by experienced providers, as good outcomes have been observed with rapid resternotomy protocols 2

Mechanical Support Options

  • For patients refractory to standard resuscitation procedures, mechanical circulatory support including ECMO or cardiopulmonary bypass may improve outcomes 1, 2
  • Consider mechanical circulatory support when the suspected etiology is potentially reversible during a limited period of mechanical support 5

Respiratory Management During Resuscitation

  • Use lower tidal volumes, lower respiratory rates, and increased expiratory time to minimize risk of auto-PEEP and barotrauma 3, 6
  • Evaluate for tension pneumothorax, which can be a rare but life-threatening complication 3, 6
  • Brief disconnection from the ventilator or pause in bag-mask ventilation with thoracic compression may relieve hyperinflation if present 3

Special Considerations

  • Cardiac arrest occurs in 1-8% of cardiac surgery cases, typically in highly monitored settings with trained staff available 1, 2
  • For patients with epicardial pacing wires, immediate pacing should be attempted before external cardiac massage in cases of asystole or extreme bradycardia 7

Pitfalls to Avoid

  • Failure to recognize mechanical causes of arrest (tamponade, bleeding, graft occlusion) that require surgical intervention 1