Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/26/2025

Chronic Lower Back Pain Management

Nonpharmacologic Therapies

  • Exercise therapy has good evidence of moderate efficacy for chronic low back pain and should be a cornerstone of treatment 1, 2
  • Spinal manipulation shows moderate effectiveness for pain relief and functional improvement 1, 3
  • Massage therapy provides fair evidence of effectiveness for chronic low back pain 3, 4
  • Acupuncture has fair evidence supporting its effectiveness for chronic pain 2, 4
  • Yoga (particularly Viniyoga) shows moderate evidence of effectiveness 2, 6
  • Cognitive-behavioral therapy demonstrates good evidence of moderate efficacy for chronic low back pain 1, 7
  • Mindfulness-based stress reduction has moderate-quality evidence supporting its use 2, 6
  • Interdisciplinary rehabilitation (combining physical, psychological, and educational interventions) shows good evidence of effectiveness, particularly when intensive (>100 hours) 1, 7
  • Functional restoration with cognitive-behavioral components is more effective than usual care for reducing work disability 5, 7

Pharmacologic Therapies

  • NSAIDs (like ibuprofen) should be the first medication choice when pharmacologic therapy is needed, with moderate evidence showing small to moderate pain improvement 8
  • Duloxetine may be considered as a second-line option with evidence of small improvements in pain and function 8
  • Opioids should be avoided for chronic low back pain due to limited evidence of long-term efficacy and significant risks 8

Common Pitfalls to Avoid

  • Bed rest is contraindicated and can worsen outcomes 6
  • Routine imaging without specific indications can lead to unnecessary interventions 6
  • Early resort to medications before adequate trial of nonpharmacologic therapies 6, 8
  • Initiating opioid therapy without exhausting other options first 8

REFERENCES