Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/14/2025

Management of Type 2 Second-Degree AV Block (Mobitz Type II)

Diagnostic Evaluation

  • The American College of Cardiology recommends an echocardiogram as the initial evaluation for Mobitz Type II second-degree AV block to assess for structural heart disease, ventricular function, and underlying cardiac pathology 1, 2
  • An ambulatory ECG monitor (Holter) is recommended to assess the burden of block and detect progression 1
  • An exercise ECG test is recommended to evaluate the response to increased heart rate demands 1
  • The echocardiogram identifies structural heart disease that may be causing the conduction abnormality, assesses ventricular function, and guides pacing decisions 1, 3

Management

  • Referral to an electrophysiologist is essential once the initial workup is complete, as Mobitz Type II block requires permanent pacemaker implantation regardless of symptoms 1, 2, 4
  • Infranodal blocks require pacing regardless of form or symptoms because they represent disease in the His-Purkinje system with a risk of progression to complete heart block 4
  • Permanent pacing is indicated for persistent second-degree AV block in the His-Purkinje system with bilateral bundle branch block, or transient advanced second-degree infranodal AV block with associated bundle branch block 4