Administration of Glutathione with Myers' Cocktail

Special Considerations

• In patients with kidney disease, caution is warranted as high-dose parenteral glutamine (a precursor to glutathione) is contraindicated in critically ill patients with acute kidney injury or chronic kidney disease 1
• Electrolyte abnormalities are common in patients with kidney dysfunction and should be closely monitored when administering intravenous therapies 2

Practical Administration

• The stability of the mixture of glutathione with Myers' cocktail should be considered, as glutathione can be unstable in certain solutions 3

Monitoring

• Assess for changes in electrolyte balance, particularly in patients with pre-existing conditions 2