Switching from Alprazolam to Lorazepam for Anxiety Management

Dosing Considerations

• For elderly or debilitated patients, an initial dose of lorazepam 0.5mg BID is appropriate as an initial dose, according to the BMJ 1

Practical Implementation Strategy

• Consider adding lorazepam 0.5-1mg every 4-6 hours as needed for breakthrough anxiety during the transition, as suggested by the BMJ 1