Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/26/2025

Contraindications and Precautions for BiPAP Use

Absolute Contraindications

  • The American Thoracic Society recommends that BiPAP should be withheld from patients with pneumothorax as long as the pneumothorax is present, regardless of size 1
  • The American Thoracic Society suggests that positive pressure ventilation can cause progression of pneumothorax, even in patients with severe obstructive airways disease who may depend on BiPAP support 1
  • The American Thoracic Society advises that if the patient requires ventilatory support during pneumothorax, observation in the intensive care unit may be appropriate while BiPAP is withheld 1
  • The American College of Chest Physicians recommends that BiPAP should be withheld from patients with massive hemoptysis 2
  • The American College of Chest Physicians states that the positive pressure can disrupt clot formation and worsen bleeding in patients with significant hemoptysis 2
  • The European Society of Cardiology notes that BiPAP reduces blood pressure and should be used with extreme caution in hypotensive patients 3

Relative Contraindications and High-Risk Scenarios

  • The European Society of Cardiology suggests that recent myocardial infarction represents a relative contraindication for BiPAP 4
  • The American Heart Association recommends that in acute heart failure with pulmonary edema, CPAP should be preferred initially over BiPAP unless hypercapnia, coexisting COPD, or respiratory muscle fatigue is present 6

Critical Monitoring Requirements When BiPAP Is Used

  • The American Thoracic Society advises that when BiPAP is deemed appropriate despite risks, continuous monitoring of arterial oxygen saturation, blood pressure, respiratory rate, heart rate, and mental status is essential 4
  • The American College of Physicians recommends checking arterial or venous blood gas (pH, PaCO2) within 2-4 hours of initiation 6

Common Pitfalls to Avoid

  • The American College of Emergency Physicians warns that one should not delay definitive airway management (intubation) by attempting BiPAP in patients with severe hemodynamic instability or depressed consciousness 6
  • The American Thoracic Society cautions that one should not continue BiPAP in the presence of pneumothorax, even if the patient has severe underlying lung disease 1