Amlodipine Onset and Efficacy

Clinical Considerations

• The American Heart Association, as reported in Circulation Research, considers amlodipine a first-line calcium channel blocker due to its long duration of action 1

Comparison to Other Calcium Channel Blockers

• Amlodipine's gradual onset avoids dangerous rapid blood pressure drops, unlike immediate-release nifedipine, as noted in Circulation 2