Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/2/2025

Management and Treatment of Sternal Crepitus

Diagnostic Approach

  • Initial radiographs are the first-line imaging study for suspected sternal crepitus to detect soft tissue gas and bony abnormalities 2, 3
  • CT scan without contrast is recommended if radiographs show soft tissue gas, as it offers higher sensitivity for detecting the extent and compartmental location of gas 2, 3
  • MRI with contrast is the preferred imaging modality for suspected osteomyelitis to determine the extent of bone and soft tissue involvement 2, 3
  • Blood cultures and tissue/abscess cultures should be obtained to identify causative pathogens 4

Treatment Based on Etiology

For Sternal Osteomyelitis

  • Surgical debridement of all necrotic tissue is strongly recommended 1
  • For Candida sternal osteomyelitis, fluconazole 400 mg daily for at least 6 months OR an echinocandin for 2 weeks followed by fluconazole for at least 4 months 1
  • For bacterial sternal osteomyelitis, empiric therapy should cover Staphylococcus aureus with vancomycin until culture results are available 4

For Soft Tissue Infection with Crepitus

  • Prompt and aggressive surgical debridement of all necrotic tissue is essential 4, 6
  • Broad-spectrum antibiotics covering gram-positive, gram-negative, and anaerobic organisms should be administered 4, 6
  • Vancomycin plus an agent active against gram-negative bacilli is recommended for initial empirical therapy 4

Special Considerations

  • Patients with diabetes or immunocompromised status may require more aggressive surgical debridement and longer courses of antimicrobial therapy 6
  • Post-sternotomy infections require careful evaluation of sternal stability; rigid sternal fixation may be beneficial in some cases to improve healing and reduce complications 7

Follow-up and Monitoring

  • Serial imaging (CT or MRI) may be necessary to evaluate treatment response in cases of osteomyelitis 2
  • For patients with implanted hardware, long-term suppressive antibiotics may be required if complete removal is not possible 1, 5

Common Pitfalls to Avoid

  • Failure to identify and address underlying risk factors may lead to poor outcomes 6
  • Overlooking the possibility of polymicrobial infection; cultures should be taken before starting antibiotics 4