Ototoxicity Associated with Capmatinib

Introduction to Ototoxicity

• Aminoglycoside-induced hearing loss is often irreversible, as documented by the American Thoracic Society 1, 2 and the British Thoracic Society 3, 4

Comparison with Other Ototoxic Agents

• The reversibility of capmatinib-associated hearing loss is currently unknown, in contrast to aminoglycoside-induced hearing loss, which is well-documented as often irreversible, according to the American Journal of Respiratory and Critical Care Medicine 1, 2 and Thorax 3, 4