Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/28/2025

Management of High Output Ileostomy

Initial Assessment

  • Determine the remaining length of bowel through contrast studies to help predict outcomes and guide nutritional support 1
  • Examine stoma output characteristics to assess severity 1
  • Exclude other causes of high output, including intra-abdominal sepsis 2, enteritis 1, recurrent disease in remaining bowel 2, and sudden discontinuation of medications 1
  • Monitor fluid output and urine sodium to guide fluid management 4

Fluid Management

  • Initially administer intravenous normal saline with the patient kept nil by mouth to demonstrate output is driven by oral intake 1
  • Restrict oral hypotonic fluids to less than 500 ml daily 1, 2
  • Encourage drinking glucose-saline replacement solution with sodium concentration of at least 90 mmol/L 1, 2
  • Use modified WHO cholera rehydration solution or alternative rehydration solution with higher sodium concentration 1, 3

Medication Management

  • Administer loperamide 2-8 mg before meals to reduce motility and stoma output 2
  • Consider adding codeine phosphate if loperamide alone is insufficient 2
  • Use drugs that reduce gastric acid secretion for secretory output 2
  • Correct hypokalaemia by addressing sodium/water depletion and normalizing serum magnesium 1, 3

Nutritional Considerations

  • Maintain adequate nutrition while managing fluid balance 4
  • Add salt to diet to the limit of palatability 1
  • Consider adding sodium chloride to liquid feeds to achieve sodium concentration near 100 mmol/L 2

Monitoring Parameters

  • Aim for daily urine volume of at least 800 ml with sodium concentration >20 mmol/L 1
  • Monitor hydration status, body weight, and electrolytes regularly 1, 4

Common Pitfalls to Avoid

  • Avoid encouraging patients to drink hypotonic solutions to quench thirst, which paradoxically increases stomal sodium losses 1, 2
  • Correct magnesium deficiency to prevent hypokalemia 5
  • Avoid administering excessive intravenous fluids, which can cause edema 1

Long-term Management

  • Combine oral fluid restriction with increased dietary salt for patients with marginally high stoma outputs 1
  • Consider continued parenteral or subcutaneous saline in the home setting for patients with ongoing high output 4
  • Implement multidisciplinary intestinal rehabilitation for successful long-term management 4