Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/10/2025

Best Medication for Conversion Disorder

Understanding Conversion Disorder

  • Symptoms of conversion disorder typically worsen with attention and improve with distraction, often developing in the context of injury, illness, or psychological distress, though psychological factors may not always be apparent 1

First-Line Treatment Approach

  • Psychotherapy, not medication, is the first-line treatment for conversion disorder, as there is no evidence supporting significant benefit from pharmacotherapy specifically for functional symptoms, and Cognitive Behavioral Therapy (CBT) shows benefit for patients with functional neurological symptoms 1
  • Clear, empathetic explanation of the diagnosis that acknowledges the involuntary nature of symptoms is crucial for treatment success 1

Specific Therapeutic Techniques

  • Imagery Rehearsal Therapy may be adapted for certain conversion symptoms 2
  • For functional tremor specifically, rhythm modification techniques and entrainment can be effective 1

Role of Medication in Conversion Disorder

  • Unlike other conditions, there is no evidence supporting significant benefit from pharmacotherapy specifically for functional symptoms, and medication should be limited to treating comorbid conditions rather than targeting conversion symptoms directly 1

Multidisciplinary Approach

  • Minimizing the use of adaptive equipment is recommended, as aids are generally unhelpful in the rehabilitation process for functional disorders 1

Treatment Pitfalls to Avoid

  • Reinforcing illness behavior by excessive focus on symptoms or providing unnecessary aids should be avoided 1
  • Dismissive approaches that fail to acknowledge the involuntary nature of symptoms should be avoided 1

REFERENCES

1

Treatment Approach for Tremor in Conversion Disorder [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

best practice guide for the treatment of nightmare disorder in adults. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010