Antibiotic Treatment for Corynebacterium spp. Infections

First-Line Treatment Options

• Vancomycin is the first-line antibiotic treatment for Corynebacterium spp. infections, particularly for severe infections or multidrug-resistant strains, as recommended by the Infectious Diseases Society of America 1
• For C. jeikeium infections specifically, vancomycin is required as this species is typically multidrug-resistant, according to the Clinical Microbiology and Infection guidelines 1

Treatment of Coryneform Gram-Positive Rod Infections

Treatment Duration

• The Infectious Diseases Society of America recommends administering therapy for 7-14 days for most serious Gram-positive infections 2
• The Infectious Diseases Society of America suggests extending duration beyond 14 days if endovascular infection or metastatic infection is present 2