Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 6/14/2025

Diagnosis and Management of Red Birthmarks

Introduction to Red Birthmarks

  • Red birthmarks should be evaluated by a specialist for proper diagnosis and treatment, with infantile hemangiomas requiring prompt referral to a hemangioma specialist if identified as high-risk, according to the American Academy of Pediatrics 1
  • Infantile hemangiomas are the most common vascular tumors of childhood, characterized by abnormal proliferation of endothelial cells, and high-risk IHs include those in the facial area, large segmental IHs, IHs causing functional impairment, IHs at risk for ulceration, and IHs with potential for permanent disfigurement, as recommended by the American Academy of Pediatrics 1

Diagnosis and Evaluation

  • Ultrasonography is the initial imaging modality when diagnosis is uncertain, and MRI may be needed for suspected deeper involvement or associated anomalies, as suggested by the American Academy of Pediatrics 1
  • The optimal time for referral or initiation of treatment is between 5-7 weeks of age, when IHs typically enter a period of rapid growth, according to the American Academy of Pediatrics 1

Management of Infantile Hemangiomas

  • Observation is appropriate for low-risk, uncomplicated IHs, as recommended by the American Academy of Pediatrics 1
  • All high-risk IHs should be referred to a hemangioma specialist as soon as possible, and telemedicine may be used for initial triage and evaluation, according to the American Academy of Pediatrics 1
  • Delayed referral can lead to permanent complications, emphasizing the importance of early intervention in high-risk IHs, as noted by the American Academy of Pediatrics 1

Patient Support and Education

  • Consider psychological support for children and families dealing with visible birthmarks, and patient advocacy groups can provide valuable support, as suggested by the American Academy of Pediatrics 2

Common Pitfalls in Diagnosis and Management

  • Misdiagnosis can occur when confusing congenital hemangiomas with infantile hemangiomas, which are fully formed at birth and don't exhibit postnatal proliferation, as noted by the American Academy of Pediatrics 3
  • Unnecessary treatment can occur when treating low-risk, uncomplicated IHs that would resolve spontaneously without intervention, highlighting the need for proper evaluation and diagnosis, according to the American Academy of Pediatrics 1