Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/10/2025

Phenobarbital IV to Oral Conversion Ratio

Clinical Application

  • For status epilepticus treatment, the American Academy of Pediatrics recommends an IV loading dose of 20 mg/kg (maximum 1000 mg) and the same dose can be used orally when IV access is not available or when transitioning to maintenance therapy 1