Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/24/2025

Chronic Idiopathic Constipation Management

First-Line Treatment Recommendations

  • The American Gastroenterological Association recommends polyethylene glycol (PEG) as a first-line treatment for chronic idiopathic constipation, with a starting dose and titration based on symptom response 1
  • The American Gastroenterological Association suggests magnesium oxide as an alternative first-line treatment, with a daily dose of 400-500 mg 1
  • The American Gastroenterological Association recommends bisacodyl for short-term or rescue use in chronic idiopathic constipation, with a daily dose of 5 mg 1