Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/1/2025

Lithium's Therapeutic Effects in Bipolar Disorder

Clinical Implications

  • The American Academy of Neurology and Psychiatry suggests that lithium reduces aggression and impulsivity while regulating stress response, which contributes to anxiety symptom improvement 1
  • Lithium possesses unique anti-suicidal properties that are independent of its mood-stabilizing effects, setting it apart from other agents, according to the National Institute of Mental Health 1