Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/10/2025

Management of Hypovolemic Shock in Gunshot Wound Patients

Initial Assessment and Classification

  • The American College of Surgeons recommends assessing the extent of traumatic hemorrhage using established grading systems such as the ATLS classification of blood loss severity 3, 4
  • Classify shock severity based on blood loss parameters, with Class I being <750 ml (15% blood volume), HR <100, normal BP, Class II being 750-1500 ml (15-30%), HR 100-120, normal BP, Class III being 1500-2000 ml (30-40%), HR 120-140, decreased BP, and Class IV being >2000 ml (>40%), HR >140, decreased BP 5, 4, 6
  • Evaluate response to initial fluid resuscitation, with rapid response being return to normal vital signs, minimal blood loss (10-20%), transient response being temporary improvement followed by deterioration, moderate ongoing blood loss (20-40%), and minimal/no response being persistently abnormal vital signs, severe blood loss (>40%) 2

Immediate Interventions

  • Identify the source of bleeding immediately through clinical assessment, and perform urgent clinical assessment of chest, abdomen, and pelvic ring stability if the source is unknown 1, 3, 8, 5
  • Use early focused sonography (FAST) to detect free intraabdominal fluid, and consider urgent surgery for patients with significant free intraabdominal fluid and hemodynamic instability 1
  • Begin crystalloid fluid therapy immediately for the hypotensive bleeding trauma patient, targeting systolic blood pressure of 80-100 mmHg until major bleeding is controlled (permissive hypotension) 9, 1

Damage Control Surgery

  • Employ damage control surgery in severely injured patients with deep hemorrhagic shock, signs of ongoing bleeding and coagulopathy, hypothermia and acidosis, inaccessible major anatomic injury, or need for time-consuming procedures 1, 10

Vasopressors and Inotropic Agents

  • Consider norepinephrine for patients with persistent hypotension despite adequate fluid resuscitation, with the goal of maintaining systolic BP 80-100 mmHg 10, 1

Additional Management Considerations

  • Avoid hyperventilation or excessive positive end-expiratory pressure in severely hypovolemic patients, and consider antifibrinolytic agents such as tranexamic acid 1, 2
  • Perform immediate pelvic ring closure and stabilization for pelvic ring disruption with hemorrhagic shock, and consider angiographic embolization or surgical bleeding control for ongoing hemodynamic instability despite pelvic ring stabilization 1
  • Avoid excessive crystalloid administration, which can worsen coagulopathy and lead to abdominal compartment syndrome, and avoid hypertonic solutions in patients with severe head trauma 9