Periorbital Edema Management

Causes and Associated Conditions

Imatinib can cause periorbital edema in up to 70% of treated patients, according to the American Society of Clinical Oncology 1
Ultrasound biomicroscopy is particularly helpful in congenital and traumatic cases of periorbital edema, as recommended by the American Academy of Ophthalmology 2
Anterior segment OCT can visualize deeper structures when edema is present, as suggested by the American Academy of Ophthalmology 3

The American Academy of Ophthalmology recommends considering the onset pattern, including acute vs. gradual development, unilateral vs. bilateral presentation, and diurnal variation, when evaluating periorbital edema 2
Imaging studies, such as ultrasound biomicroscopy and anterior segment OCT, should be used when needed to evaluate periorbital edema, as recommended by the American Academy of Ophthalmology 2, 3

The American Academy of Ophthalmology recommends topical or systemic antibiotics for infectious causes of periorbital edema, and prophylactic broad-spectrum antibiotics should be considered when using bandage contact lenses 2
For imatinib-induced periorbital edema, diuretics have limited benefit, according to the American Society of Clinical Oncology 1
The American Academy of Ophthalmology suggests using hyperosmotic agents like sodium chloride 5% drops or ointment for symptomatic management of periorbital edema 2, 3