Motion Sickness Treatment Options

Pharmacological Treatment Options

• Meclizine is commonly used for peripheral vertigo and motion sickness symptoms, according to the American College of Medical Toxicology 1

Second-Line Options

• Prokinetic antiemetics such as metoclopramide can be useful adjuncts for managing nausea and vomiting associated with motion sickness, as recommended by the American Academy of Neurology 2
• Prochlorperazine may be used for short-term management of severe nausea or vomiting in patients with motion sickness who are severely symptomatic, as suggested by the American College of Medical Toxicology 3

Special Considerations

• Vestibular suppressant medications should be used for short-term management rather than long-term treatment, according to the American College of Medical Toxicology 1, 3

Pitfalls and Caveats

• Long-term use of vestibular suppressant medications can interfere with natural adaptation to motion, as warned by the American College of Medical Toxicology 1
• Medications primarily treat symptoms rather than addressing the underlying sensory conflict, as noted by the American College of Medical Toxicology 3