Cyproheptadine Dosing for Pediatric Patients

Special Considerations for Specific Indications

• For treatment of serotonin syndrome in pediatric patients, the American Academy of Pediatrics recommends a dosage of 0.25 mg/kg per day, with cyproheptadine being the preferred agent over other options 1, 2
• When administering cyproheptadine, it is available as 4 mg tablets that can be divided for smaller doses, and tablets can be crushed and administered via nasogastric tube if needed, as suggested by the Pediatrics guidelines 1, 2