Ozone Therapy Safety and Toxicity

Toxicity of Ozone Inhalation

• Exposure to ozone at 0.1 ppm stimulates the upper respiratory tract and urinary tract 1, 2, 3
• Exposure to ozone at 1.0-2.0 ppm causes rhinitis, cough, nausea, vomiting, and asthma 1, 2, 3
• Exposure to ozone at 2-5 ppm leads to difficulty breathing, bronchospasm, and retrosternal pain after 10-20 minutes of inhalation 1, 2, 3
• Exposure to ozone at 10 ppm can cause death after 4 hours of inhalation 1, 2, 3
• Exposure to ozone at 50 ppm can cause death in minutes 1, 2, 3

Regulatory Exposure Limits

• The EPA (United States Environmental Protection Agency) sets a limit of 0.08 ppm for 8 hours 3
• OSHA (Occupational Safety and Health Administration) sets a limit of 0.10 ppm for 8 hours 2
• The FDA (Food and Drug Administration) sets a limit of 0.05 ppm for 8 hours 2