Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/24/2025

Management of Postural Orthostatic Tachycardia Syndrome in Pregnancy

Pharmacological Management

  • The European Heart Association recommends avoiding atenolol due to intrauterine growth retardation risk 2
  • The American College of Cardiology suggests propranolol or metoprolol as first-line pharmacological agents for POTS in pregnancy 1

Postpartum Considerations

  • The European Heart Journal notes that symptoms may worsen immediately postpartum due to rapid fluid shifts and autotransfusion from uterine involution 2

Multidisciplinary Team Approach

  • The European Heart Journal recommends establishing a care plan early in pregnancy with a multidisciplinary team, including maternal-fetal medicine, cardiology, anesthesiology, and autonomic specialists 2

Common Pitfalls to Avoid

  • The American College of Cardiology advises against using atenolol for rate control in pregnancy 1, 2