Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/13/2025

Equivalent Dose of Vyvanse for 20mg Adderall

Conversion Rationale

  • The American College of Obstetricians and Gynecologists recommends a starting dose for Vyvanse of 20-30mg once daily, which can be increased by 10mg weekly to a maximum of 70mg daily 1, 2
  • The usual starting dose for Adderall is 10mg once daily, which can be titrated by 5mg weekly up to 50mg 1

Dosing Algorithm

  • A conversion factor of approximately 2.5:1 (Vyvanse:Adderall) can be applied when converting from Adderall to Vyvanse, resulting in a dose of 50mg Vyvanse for a patient taking 20mg of Adderall 1, 2

Monitoring and Adjustments

  • The maximum recommended dose of Vyvanse is 70mg daily, and dosage can be adjusted in 10mg increments at weekly intervals if needed 1, 2

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