Intramuscular Administration of Ranitidine

Administration Guidelines

• The Mayo Clinic Proceedings recommends administering intramuscular injections in the gluteal region, specifically in the posterior lateral aspect of the upper buttocks, to avoid major nerves and blood vessels 1
• For stress ulcer prophylaxis in critically ill patients, the American Society of Critical Care Medicine defines "low-dose" H2RA therapy as a daily dose of ≤40mg famotidine, ≤150mg IV ranitidine, or ≤300mg enteral ranitidine 2

Injection Technique

• To avoid sciatic nerve injury, the Mayo Clinic Proceedings recommends using the upper outer quadrant of the buttock when administering intramuscular injections in the gluteal region 1