Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/25/2025

Timing of Coombs Test After Blood Transfusion in Neonates

Special Considerations in Neonates

  • For neonatal testing with suspected congenital toxoplasmosis, if blood product transfusion or IVIg has been given, repeat Toxoplasma IgM testing at least 7 days after the last transfusion to avoid false-positive results, as recommended by the Pediatrics guideline society 1
  • Toxoplasma IgA testing should be repeated at least 7 days after transfusion if false-positive results from blood product contamination are suspected, according to the Pediatrics guideline society 1