Treatment of Acne in Teenagers with Sarecycline

Efficacy and Recommendations

The American Academy of Dermatology conditionally recommends sarecycline as a systemic antibiotic option for moderate to severe acne in adolescents and preadolescents (≥9 years) 1, 2

For moderate to severe acne with inadequate response to topical therapy after 6-8 weeks, the American Academy of Dermatology suggests adding oral antibiotic therapy, with sarecycline being a good option for teenagers ≥9 years old 2
The American Academy of Dermatology recommends limiting systemic antibiotic use to the shortest possible duration (ideally ≤3 months) to minimize risk of bacterial resistance 2
Consider the psychological impact of acne when determining treatment aggressiveness, as acne can significantly affect quality of life in teenagers 4